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Forum Briefing Room No excipient used in such small quantities can

No excipient used in such small quantities can

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8:17 pm
30 December, 2011


tvxqliuli

New Member

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1

No excipient used in such small quantities can have as detrimental effect on tablet quality than magnesium stearate. Magnesium stearate, although a very effective lubricant, can reduce the mechanical strength of the cores, decrease film adhesion and slow drug dissolution. Therefore, the quantity of magnesium stearate used in  The North Face Denali Jacket   a tablet formulation should be minimized. Self-lubricating products such as Starch 1500 can also be used to reduce the need for significant lubricant addition.

 

Conclusion

 

Many of the ingredients chosen in initial tablet formulation  North Face Denali Hoodie   development can have a significant impact on aqueous film coating quality. They may affect the physical, mechanical, adhesive, drug-release and stability properties of the coated dosage form.

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